CALL FOR PAPERS Mitochondria in Cardiovascular Physiology and Disease Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival
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چکیده
Tatiana F. Galvao, Ramzi J. Khairallah, Erinne R. Dabkowski, Bethany H. Brown, Peter A. Hecker, Kelly A. O’Connell, Karen M. O’Shea, Hani N. Sabbah, Sharad Rastogi, Caroline Daneault, Christine Des Rosiers, and William C. Stanley Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, Maryland; Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Michigan; and Department of Nutrition and Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada
منابع مشابه
Review Article: The importance of Omega-3 fatty acids in fish on human health
Heart failure (HF) incidence increases worldwide and is affected by various risk factors such as coronary artery disease, hypertension, obesity, and diabetes. Dietary recommendations for patients with HF have generally focused on sodium restriction; however, different nutritional approaches are considered in patients with a high risk of malnutrition due to the diuretic drugs they use. Omega-3 f...
متن کاملDietary saturated fat and docosahexaenoic acid differentially effect cardiac mitochondrial phospholipid fatty acyl composition and Ca2+ uptake, without altering permeability transition or left ventricular function
High saturated fat diets improve cardiac function and survival in rodent models of heart failure, which may be mediated by changes in mitochondrial function. Dietary supplementation with the n3-polyunsaturated fatty acid docosahexaenoic acid (DHA, 22:6n3) is also beneficial in heart failure and can affect mitochondrial function. Saturated fatty acids and DHA likely have opposing effects on mito...
متن کاملDietary saturated fat and docosahexaenoic acid differentially effect cardiac mitochondrial phospholipid fatty acyl composition and Ca uptake, without altering permeability transition or left ventricular function
High saturated fat diets improve cardiac function and survival in rodent models of heart failure, which may be mediated by changes in mitochondrial function. Dietary supplementation with the n3-polyunsaturated fatty acid docosahexaenoic acid (DHA, 22:6n3) is also beneficial in heart failure and can affect mitochondrial function. Saturated fatty acids and DHA likely have opposing effects on mito...
متن کاملHigh intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects.
AIMS The impact of a high-fat diet on the failing heart is unclear, and the differences between polyunsaturated fatty acids (PUFA) and saturated fat have not been assessed. Here, we compared a standard low-fat diet to high-fat diets enriched with either saturated fat (palmitate and stearate) or PUFA (linoleic and α-linolenic acids) in hamsters with genetic cardiomyopathy. METHODS AND RESULTS ...
متن کاملEffects of enriched Artemia with n–3 long-chain polyunsaturated fatty acids on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei postlarvae
A 15-day study was conducted to evaluate the effects of Artemia metanauplii enriched with two commercial supplements (Easy DHA-Selco and S. presso) which contained high levels of n–3 long chain polyunsaturated fatty acids (n–3 LC-PUFA) on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei post larvae (PL). In this regard, PL were fed with three different types ...
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تاریخ انتشار 2012